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Limiting glucocorticoid secretion increases the anorexigenic property of Exendin-4
OBJECTIVE: Glucagon-like peptide-1 (GLP-1) analogs are attractive options for the treatment of type II diabetes and obesity because of their incretin and anorexigenic effects. Peripheral administration of the GLP-1R agonist Exendin-4 (Ex-4) also increases glucocorticoid secretion in rodents and huma...
Autores principales: | Lee, Shin J., Diener, Katharina, Kaufman, Sharon, Krieger, Jean-Philippe, Pettersen, Klaus G., Jejelava, Nino, Arnold, Myrtha, Watts, Alan G., Langhans, Wolfgang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4921942/ https://www.ncbi.nlm.nih.gov/pubmed/27408779 http://dx.doi.org/10.1016/j.molmet.2016.04.008 |
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