Metabolic reprogramming through fatty acid transport protein 1 (FATP1) regulates macrophage inflammatory potential and adipose inflammation

OBJECTIVE: A novel approach to regulate obesity-associated adipose inflammation may be through metabolic reprogramming of macrophages (MΦs). Broadly speaking, MΦs dependent on glucose are pro-inflammatory, classically activated MΦs (CAM), which contribute to adipose inflammation and insulin resistan...

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Detalles Bibliográficos
Autores principales: Johnson, Amy R., Qin, Yuanyuan, Cozzo, Alyssa J., Freemerman, Alex J., Huang, Megan J., Zhao, Liyang, Sampey, Brante P., Milner, J. Justin, Beck, Melinda A., Damania, Blossom, Rashid, Naim, Galanko, Joseph A., Lee, Douglas P., Edin, Matthew L., Zeldin, Darryl C., Fueger, Patrick T., Dietz, Brittney, Stahl, Andreas, Wu, Ying, Mohlke, Karen L., Makowski, Liza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4921943/
https://www.ncbi.nlm.nih.gov/pubmed/27408776
http://dx.doi.org/10.1016/j.molmet.2016.04.005

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