Cargando…
Bivalent vaccine platform based on Japanese encephalitis virus (JEV) elicits neutralizing antibodies against JEV and hepatitis C virus
Directly acting antivirals recently have become available for the treatment of hepatitis C virus (HCV) infection, but there is no prophylactic vaccine for HCV. In the present study, we took advantage of the properties of Japanese encephalitis virus (JEV) to develop antigens for use in a HCV vaccine....
Autores principales: | Saga, Ryohei, Fujimoto, Akira, Watanabe, Noriyuki, Matsuda, Mami, Hasegawa, Makoto, Watashi, Koichi, Aizaki, Hideki, Nakamura, Noriko, Tajima, Shigeru, Takasaki, Tomohiko, Konishi, Eiji, Kato, Takanobu, Kohara, Michinori, Takeyama, Haruko, Wakita, Takaji, Suzuki, Ryosuke |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4922013/ https://www.ncbi.nlm.nih.gov/pubmed/27345289 http://dx.doi.org/10.1038/srep28688 |
Ejemplares similares
-
Amino Acid at Position 166 of NS2A in Japanese Encephalitis Virus (JEV) Is Associated with In Vitro Growth Characteristics of JEV
por: Tajima, Shigeru, et al.
Publicado: (2020) -
Immunogenicity and Protective Ability of Genotype I-Based Recombinant Japanese Encephalitis Virus (JEV) with Attenuation Mutations in E Protein against Genotype V JEV
por: Tajima, Shigeru, et al.
Publicado: (2021) -
Comparison of JEV neutralization assay using pseudotyped JEV with the conventional plaque-reduction neutralization test
por: Lee, Hee-Jung, et al.
Publicado: (2014) -
High-throughput neutralization assay for multiple flaviviruses based on single-round infectious particles using dengue virus type 1 reporter replicon
por: Matsuda, Mami, et al.
Publicado: (2018) -
A replication-defective Japanese encephalitis virus (JEV) vaccine candidate with NS1 deletion confers dual protection against JEV and West Nile virus in mice
por: Li, Na, et al.
Publicado: (2020)