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Loss of flotillin expression results in weakened desmosomal adhesion and Pemphigus vulgaris-like localisation of desmoglein-3 in human keratinocytes

Desmosomes are adhesion plaques that mediate cell-cell adhesion in many tissues, including the epidermis, and generate mechanical resistance to tissues. The extracellular domains of desmosomal cadherin proteins, desmogleins and desmocollins, are required for the interaction with cadherins of the nei...

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Detalles Bibliográficos
Autores principales: Völlner, Frauke, Ali, Jawahir, Kurrle, Nina, Exner, Yvonne, Eming, Rüdiger, Hertl, Michael, Banning, Antje, Tikkanen, Ritva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4922016/
https://www.ncbi.nlm.nih.gov/pubmed/27346727
http://dx.doi.org/10.1038/srep28820