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Loss of flotillin expression results in weakened desmosomal adhesion and Pemphigus vulgaris-like localisation of desmoglein-3 in human keratinocytes
Desmosomes are adhesion plaques that mediate cell-cell adhesion in many tissues, including the epidermis, and generate mechanical resistance to tissues. The extracellular domains of desmosomal cadherin proteins, desmogleins and desmocollins, are required for the interaction with cadherins of the nei...
Autores principales: | Völlner, Frauke, Ali, Jawahir, Kurrle, Nina, Exner, Yvonne, Eming, Rüdiger, Hertl, Michael, Banning, Antje, Tikkanen, Ritva |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4922016/ https://www.ncbi.nlm.nih.gov/pubmed/27346727 http://dx.doi.org/10.1038/srep28820 |
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