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DJ-1 deficiency impairs glutamate uptake into astrocytes via the regulation of flotillin-1 and caveolin-1 expression

Parkinson’s disease (PD) is a common chronic and progressive neurodegenerative disorder. Although the cause of PD is still poorly understood, mutations in many genes including SNCA, parkin, PINK1, LRRK2, and DJ-1 have been identified in the familial forms of PD. It was recently proposed that alterat...

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Detalles Bibliográficos
Autores principales: Kim, Jin-Mo, Cha, Seon-Heui, Choi, Yu Ree, Jou, Ilo, Joe, Eun-Hye, Park, Sang Myun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4922019/
https://www.ncbi.nlm.nih.gov/pubmed/27346864
http://dx.doi.org/10.1038/srep28823

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