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Adolescent idiopathic scoliosis: current concepts on neurological and muscular etiologies
Adolescent idiopathic scoliosis (AIS) is a frequent disease but its etiology remains unknown. Gender prevalence in females is already known and there are many suggested hypotheses to explain its origin and manifestation, like associated neurologic, muscular and connective tissue disorders. Literatur...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4922065/ https://www.ncbi.nlm.nih.gov/pubmed/27355084 http://dx.doi.org/10.1186/s13013-016-0066-y |
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author | Wajchenberg, Marcelo Astur, Nelson Kanas, Michel Martins, Délio Eulálio |
author_facet | Wajchenberg, Marcelo Astur, Nelson Kanas, Michel Martins, Délio Eulálio |
author_sort | Wajchenberg, Marcelo |
collection | PubMed |
description | Adolescent idiopathic scoliosis (AIS) is a frequent disease but its etiology remains unknown. Gender prevalence in females is already known and there are many suggested hypotheses to explain its origin and manifestation, like associated neurologic, muscular and connective tissue disorders. Literature reports have tried to analyze disease prevalence in selected populations, possible ways of inheritance, related genes location and their polymorphisms, which may play a role in the development of the deformity. The purpose of this paper is to review and update concepts on the origin and genetic influence on AIS. |
format | Online Article Text |
id | pubmed-4922065 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-49220652016-06-28 Adolescent idiopathic scoliosis: current concepts on neurological and muscular etiologies Wajchenberg, Marcelo Astur, Nelson Kanas, Michel Martins, Délio Eulálio Scoliosis Spinal Disord Review Adolescent idiopathic scoliosis (AIS) is a frequent disease but its etiology remains unknown. Gender prevalence in females is already known and there are many suggested hypotheses to explain its origin and manifestation, like associated neurologic, muscular and connective tissue disorders. Literature reports have tried to analyze disease prevalence in selected populations, possible ways of inheritance, related genes location and their polymorphisms, which may play a role in the development of the deformity. The purpose of this paper is to review and update concepts on the origin and genetic influence on AIS. BioMed Central 2016-06-27 /pmc/articles/PMC4922065/ /pubmed/27355084 http://dx.doi.org/10.1186/s13013-016-0066-y Text en © Wajchenberg et al. 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Review Wajchenberg, Marcelo Astur, Nelson Kanas, Michel Martins, Délio Eulálio Adolescent idiopathic scoliosis: current concepts on neurological and muscular etiologies |
title | Adolescent idiopathic scoliosis: current concepts on neurological and muscular etiologies |
title_full | Adolescent idiopathic scoliosis: current concepts on neurological and muscular etiologies |
title_fullStr | Adolescent idiopathic scoliosis: current concepts on neurological and muscular etiologies |
title_full_unstemmed | Adolescent idiopathic scoliosis: current concepts on neurological and muscular etiologies |
title_short | Adolescent idiopathic scoliosis: current concepts on neurological and muscular etiologies |
title_sort | adolescent idiopathic scoliosis: current concepts on neurological and muscular etiologies |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4922065/ https://www.ncbi.nlm.nih.gov/pubmed/27355084 http://dx.doi.org/10.1186/s13013-016-0066-y |
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