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Adolescent idiopathic scoliosis: current concepts on neurological and muscular etiologies

Adolescent idiopathic scoliosis (AIS) is a frequent disease but its etiology remains unknown. Gender prevalence in females is already known and there are many suggested hypotheses to explain its origin and manifestation, like associated neurologic, muscular and connective tissue disorders. Literatur...

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Autores principales: Wajchenberg, Marcelo, Astur, Nelson, Kanas, Michel, Martins, Délio Eulálio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4922065/
https://www.ncbi.nlm.nih.gov/pubmed/27355084
http://dx.doi.org/10.1186/s13013-016-0066-y
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author Wajchenberg, Marcelo
Astur, Nelson
Kanas, Michel
Martins, Délio Eulálio
author_facet Wajchenberg, Marcelo
Astur, Nelson
Kanas, Michel
Martins, Délio Eulálio
author_sort Wajchenberg, Marcelo
collection PubMed
description Adolescent idiopathic scoliosis (AIS) is a frequent disease but its etiology remains unknown. Gender prevalence in females is already known and there are many suggested hypotheses to explain its origin and manifestation, like associated neurologic, muscular and connective tissue disorders. Literature reports have tried to analyze disease prevalence in selected populations, possible ways of inheritance, related genes location and their polymorphisms, which may play a role in the development of the deformity. The purpose of this paper is to review and update concepts on the origin and genetic influence on AIS.
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spelling pubmed-49220652016-06-28 Adolescent idiopathic scoliosis: current concepts on neurological and muscular etiologies Wajchenberg, Marcelo Astur, Nelson Kanas, Michel Martins, Délio Eulálio Scoliosis Spinal Disord Review Adolescent idiopathic scoliosis (AIS) is a frequent disease but its etiology remains unknown. Gender prevalence in females is already known and there are many suggested hypotheses to explain its origin and manifestation, like associated neurologic, muscular and connective tissue disorders. Literature reports have tried to analyze disease prevalence in selected populations, possible ways of inheritance, related genes location and their polymorphisms, which may play a role in the development of the deformity. The purpose of this paper is to review and update concepts on the origin and genetic influence on AIS. BioMed Central 2016-06-27 /pmc/articles/PMC4922065/ /pubmed/27355084 http://dx.doi.org/10.1186/s13013-016-0066-y Text en © Wajchenberg et al. 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Review
Wajchenberg, Marcelo
Astur, Nelson
Kanas, Michel
Martins, Délio Eulálio
Adolescent idiopathic scoliosis: current concepts on neurological and muscular etiologies
title Adolescent idiopathic scoliosis: current concepts on neurological and muscular etiologies
title_full Adolescent idiopathic scoliosis: current concepts on neurological and muscular etiologies
title_fullStr Adolescent idiopathic scoliosis: current concepts on neurological and muscular etiologies
title_full_unstemmed Adolescent idiopathic scoliosis: current concepts on neurological and muscular etiologies
title_short Adolescent idiopathic scoliosis: current concepts on neurological and muscular etiologies
title_sort adolescent idiopathic scoliosis: current concepts on neurological and muscular etiologies
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4922065/
https://www.ncbi.nlm.nih.gov/pubmed/27355084
http://dx.doi.org/10.1186/s13013-016-0066-y
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