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Upper alveolar brown tumor as initial presentation of parathyroid adenoma

Parathyroid adenoma usually presents with the signs and symptoms of hypercalcemia due to hyperparathyroidism. Brown's tumor is the late clinical consequence of untreated hyperparathyroidism and is rarely seen now-a-days due to improved screening biochemical tests. These tumors are characterized...

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Autores principales: Hakeem, Arsheed Hussain, Hakeem, Imtiyaz Hussain, Wani, Fozia Jeelani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4922239/
https://www.ncbi.nlm.nih.gov/pubmed/27390503
http://dx.doi.org/10.4103/0975-5950.183865
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author Hakeem, Arsheed Hussain
Hakeem, Imtiyaz Hussain
Wani, Fozia Jeelani
author_facet Hakeem, Arsheed Hussain
Hakeem, Imtiyaz Hussain
Wani, Fozia Jeelani
author_sort Hakeem, Arsheed Hussain
collection PubMed
description Parathyroid adenoma usually presents with the signs and symptoms of hypercalcemia due to hyperparathyroidism. Brown's tumor is the late clinical consequence of untreated hyperparathyroidism and is rarely seen now-a-days due to improved screening biochemical tests. These tumors are characterized by high orthoclastic activity and bone resorption. These are usually located in the pelvis, ribs, clavicles, and extremities. This manuscript highlights a rare presentation of brown's tumor of upper alveolus in a 35-year-old female with a previously undiagnosed case of hyperparathyroidism due to a parathyroid adenoma. Blood analysis depicted high levels of serum calcium and parathyroid hormone. The patient was subjected to selective left lower parathyroidectomy and will receive follow-up to prevent further developments of the disease. Clinicians should be aware of such rare presentation of parathyroid adenomas so that unnecessary extensive surgery of brown's tumor is avoided. This case also highlights the need of detailed work up to arrive at an exact diagnosis and direct surgical intervention to the adenoma rather the secondary manifestation of the disease.
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spelling pubmed-49222392016-07-07 Upper alveolar brown tumor as initial presentation of parathyroid adenoma Hakeem, Arsheed Hussain Hakeem, Imtiyaz Hussain Wani, Fozia Jeelani Natl J Maxillofac Surg Case Report Parathyroid adenoma usually presents with the signs and symptoms of hypercalcemia due to hyperparathyroidism. Brown's tumor is the late clinical consequence of untreated hyperparathyroidism and is rarely seen now-a-days due to improved screening biochemical tests. These tumors are characterized by high orthoclastic activity and bone resorption. These are usually located in the pelvis, ribs, clavicles, and extremities. This manuscript highlights a rare presentation of brown's tumor of upper alveolus in a 35-year-old female with a previously undiagnosed case of hyperparathyroidism due to a parathyroid adenoma. Blood analysis depicted high levels of serum calcium and parathyroid hormone. The patient was subjected to selective left lower parathyroidectomy and will receive follow-up to prevent further developments of the disease. Clinicians should be aware of such rare presentation of parathyroid adenomas so that unnecessary extensive surgery of brown's tumor is avoided. This case also highlights the need of detailed work up to arrive at an exact diagnosis and direct surgical intervention to the adenoma rather the secondary manifestation of the disease. Medknow Publications & Media Pvt Ltd 2015 /pmc/articles/PMC4922239/ /pubmed/27390503 http://dx.doi.org/10.4103/0975-5950.183865 Text en Copyright: © 2015 National Journal of Maxillofacial Surgery http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Case Report
Hakeem, Arsheed Hussain
Hakeem, Imtiyaz Hussain
Wani, Fozia Jeelani
Upper alveolar brown tumor as initial presentation of parathyroid adenoma
title Upper alveolar brown tumor as initial presentation of parathyroid adenoma
title_full Upper alveolar brown tumor as initial presentation of parathyroid adenoma
title_fullStr Upper alveolar brown tumor as initial presentation of parathyroid adenoma
title_full_unstemmed Upper alveolar brown tumor as initial presentation of parathyroid adenoma
title_short Upper alveolar brown tumor as initial presentation of parathyroid adenoma
title_sort upper alveolar brown tumor as initial presentation of parathyroid adenoma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4922239/
https://www.ncbi.nlm.nih.gov/pubmed/27390503
http://dx.doi.org/10.4103/0975-5950.183865
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