Thrombotic microangiopathy as an initial manifestation in HIV patients

Thrombotic microangiopathy (TMA) is characterized by microangiopathic hemolytic anemia, thrombocytopenia, microvascular thrombosis, and various organ dysfunctions. TMA usually occurs in a more advanced stage of HIV disease. TMA as an initial presenting feature is rare. We here report a male patient...

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Autores principales: Dineshkumar, Thanigachalam, Dhanapriya, Jeyachandran, Jaganathan, Palanivel, Sakthirajan, Ramanathan, Gopalakrishnan, Natarajan, Balasubramaniyan, T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4922295/
https://www.ncbi.nlm.nih.gov/pubmed/27390466
http://dx.doi.org/10.4103/0972-5229.183903
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author Dineshkumar, Thanigachalam
Dhanapriya, Jeyachandran
Jaganathan, Palanivel
Sakthirajan, Ramanathan
Gopalakrishnan, Natarajan
Balasubramaniyan, T.
author_facet Dineshkumar, Thanigachalam
Dhanapriya, Jeyachandran
Jaganathan, Palanivel
Sakthirajan, Ramanathan
Gopalakrishnan, Natarajan
Balasubramaniyan, T.
author_sort Dineshkumar, Thanigachalam
collection PubMed
description Thrombotic microangiopathy (TMA) is characterized by microangiopathic hemolytic anemia, thrombocytopenia, microvascular thrombosis, and various organ dysfunctions. TMA usually occurs in a more advanced stage of HIV disease. TMA as an initial presenting feature is rare. We here report a male patient who presented with oliguric renal failure. Investigations revealed anemia, thrombocytopenia, schistocytes in peripheral smear, and HIV-positive. Renal biopsy revealed TMA. He was treated with hemodialysis and started on highly active antiretroviral therapy.
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spelling pubmed-49222952016-07-07 Thrombotic microangiopathy as an initial manifestation in HIV patients Dineshkumar, Thanigachalam Dhanapriya, Jeyachandran Jaganathan, Palanivel Sakthirajan, Ramanathan Gopalakrishnan, Natarajan Balasubramaniyan, T. Indian J Crit Care Med Case Report Thrombotic microangiopathy (TMA) is characterized by microangiopathic hemolytic anemia, thrombocytopenia, microvascular thrombosis, and various organ dysfunctions. TMA usually occurs in a more advanced stage of HIV disease. TMA as an initial presenting feature is rare. We here report a male patient who presented with oliguric renal failure. Investigations revealed anemia, thrombocytopenia, schistocytes in peripheral smear, and HIV-positive. Renal biopsy revealed TMA. He was treated with hemodialysis and started on highly active antiretroviral therapy. Medknow Publications & Media Pvt Ltd 2016-06 /pmc/articles/PMC4922295/ /pubmed/27390466 http://dx.doi.org/10.4103/0972-5229.183903 Text en Copyright: © Indian Journal of Critical Care Medicine http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution NonCommercial ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Case Report
Dineshkumar, Thanigachalam
Dhanapriya, Jeyachandran
Jaganathan, Palanivel
Sakthirajan, Ramanathan
Gopalakrishnan, Natarajan
Balasubramaniyan, T.
Thrombotic microangiopathy as an initial manifestation in HIV patients
title Thrombotic microangiopathy as an initial manifestation in HIV patients
title_full Thrombotic microangiopathy as an initial manifestation in HIV patients
title_fullStr Thrombotic microangiopathy as an initial manifestation in HIV patients
title_full_unstemmed Thrombotic microangiopathy as an initial manifestation in HIV patients
title_short Thrombotic microangiopathy as an initial manifestation in HIV patients
title_sort thrombotic microangiopathy as an initial manifestation in hiv patients
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4922295/
https://www.ncbi.nlm.nih.gov/pubmed/27390466
http://dx.doi.org/10.4103/0972-5229.183903
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