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»Treatment Resistance« Enigma Resolved by Pharmacogenomics - A Case Study of Clozapine Therapy in Schizophrenia

The introduction of antipsychotic medication in the 1950s forever changed the outlook on the treatment of schizophrenia, although there is still a large proportion of patients who do not reach functional recovery. At least 30% of patients do not respond to clozapine, the tricyclic dibenzodiazepine w...

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Detalles Bibliográficos
Autores principales: Marić, Nadja P., Nikolić, Slobodanka Pejović, Buzadžić, Ivana, Jovičić, Milica, Andrić, Sanja, Mihaljević, Marina, Pavlović, Zorana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society of Medical Biochemists of Serbia 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4922322/
https://www.ncbi.nlm.nih.gov/pubmed/28356835
http://dx.doi.org/10.2478/jomb-2014-0041