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»Treatment Resistance« Enigma Resolved by Pharmacogenomics - A Case Study of Clozapine Therapy in Schizophrenia
The introduction of antipsychotic medication in the 1950s forever changed the outlook on the treatment of schizophrenia, although there is still a large proportion of patients who do not reach functional recovery. At least 30% of patients do not respond to clozapine, the tricyclic dibenzodiazepine w...
Autores principales: | Marić, Nadja P., Nikolić, Slobodanka Pejović, Buzadžić, Ivana, Jovičić, Milica, Andrić, Sanja, Mihaljević, Marina, Pavlović, Zorana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society of Medical Biochemists of Serbia
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4922322/ https://www.ncbi.nlm.nih.gov/pubmed/28356835 http://dx.doi.org/10.2478/jomb-2014-0041 |
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