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Influence of Promoter Polymorphisms of the TNF-α (-308G/A) and IL-6 (-174G/C) Genes on Therapeutic Response to Etanercept in Rheumatoid Arthritis
BACKGROUND: The study was undertaken to assess the influence of functional -308G/A TNF-α (rs 1800629) and -174G/C IL-6 (rs1800795) promoter polymorphisms on the therapeutic response to etanercept, a TNF-α blocker, in patients with rheumatoid arthritis (RA). METHODS: Seventy-three patients suffering...
Autores principales: | Jančić, Ivan, Šefik-Bukilica, Mirjana, Živojinović, Slađana, Damjanov, Nemanja, Spasovski, Vesna, Kotur, Nikola, Klaassen, Kristel, Pavlović, Sonja, Bufan, Biljana, Arsenović-Ranin, Nevena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society of Medical Biochemists of Serbia
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4922353/ https://www.ncbi.nlm.nih.gov/pubmed/28356850 http://dx.doi.org/10.2478/jomb-2014-0060 |
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