Development of Diubiquitin‐Based FRET Probes To Quantify Ubiquitin Linkage Specificity of Deubiquitinating Enzymes

Deubiquitinating enzymes (DUBs) are proteases that fulfill crucial roles in the ubiquitin (Ub) system, by deconjugation of Ub from its targets and disassembly of polyUb chains. The specificity of a DUB towards one of the polyUb chain linkages largely determines the ultimate signaling function. We pr...

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Detalles Bibliográficos
Autores principales: Geurink, Paul P., van Tol, Bianca D. M., van Dalen, Duco, Brundel, Paul J. G., Mevissen, Tycho E. T., Pruneda, Jonathan N., Elliott, Paul R., van Tilburg, Gabriëlle B. A., Komander, David, Ovaa, Huib
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4922411/
https://www.ncbi.nlm.nih.gov/pubmed/26996281
http://dx.doi.org/10.1002/cbic.201600017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4922411/
https://www.ncbi.nlm.nih.gov/pubmed/26996281
http://dx.doi.org/10.1002/cbic.201600017

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