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Prosurvival AMBRA1 turns into a proapoptotic BH3-like protein during mitochondrial apoptosis
Autophagy and apoptosis are 2 stress-response mechanisms that are closely interconnected. However, the molecular interplays between these 2 pathways remain to be clarified. Here we report that the crucial proautophagic factor AMBRA1 can act as a positive mediator of mitochondrial apoptosis. Indeed,...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4922440/ https://www.ncbi.nlm.nih.gov/pubmed/27123694 http://dx.doi.org/10.1080/15548627.2016.1164359 |