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ATG7 regulates energy metabolism, differentiation and survival of Philadelphia-chromosome-positive cells

A major drawback of tyrosine kinase inhibitor (TKI) treatment in chronic myeloid leukemia (CML) is that primitive CML cells are able to survive TKI-mediated BCR-ABL inhibition, leading to disease persistence in patients. Investigation of strategies aiming to inhibit alternative survival pathways in...

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Detalles Bibliográficos
Autores principales:	Karvela, Maria, Baquero, Pablo, Kuntz, Elodie M., Mukhopadhyay, Arunima, Mitchell, Rebecca, Allan, Elaine K., Chan, Edmond, Kranc, Kamil R., Calabretta, Bruno, Salomoni, Paolo, Gottlieb, Eyal, Holyoake, Tessa L., Helgason, G. Vignir
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2016
Materias:	Basic Research Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4922442/ https://www.ncbi.nlm.nih.gov/pubmed/27168493 http://dx.doi.org/10.1080/15548627.2016.1162359

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