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Evolution of the Transmission-Blocking Vaccine Candidates Pvs28 and Pvs25 in Plasmodium vivax: Geographic Differentiation and Evidence of Positive Selection

Transmission-blocking (TB) vaccines are considered an important tool for malaria control and elimination. Among all the antigens characterized as TB vaccines against Plasmodium vivax, the ookinete surface proteins Pvs28 and Pvs25 are leading candidates. These proteins likely originated by a gene dup...

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Detalles Bibliográficos
Autores principales:	Chaurio, Ricardo A., Pacheco, M. Andreína, Cornejo, Omar E., Durrego, Ester, Stanley, Craig E., Castillo, Andreína I., Herrera, Sócrates, Escalante, Ananias A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4922550/ https://www.ncbi.nlm.nih.gov/pubmed/27347876 http://dx.doi.org/10.1371/journal.pntd.0004786

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