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A Small Molecule, Which Competes with MAdCAM-1, Activates Integrin α(4)β(7) and Fails to Prevent Mucosal Transmission of SHIV-SF162P3
Mucosal HIV-1 transmission is inefficient. However, certain viral and host characteristics may play a role in facilitating HIV acquisition and systemic expansion. Cells expressing high levels of integrin α(4)β(7) have been implicated in favoring the transmission process and the infusion of an anti-α...
Autores principales: | Arrode-Brusés, Géraldine, Goode, Diana, Kleinbeck, Kyle, Wilk, Jolanta, Frank, Ines, Byrareddy, Siddappa, Arthos, James, Grasperge, Brooke, Blanchard, James, Zydowsky, Thomas, Gettie, Agegnehu, Martinelli, Elena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4922556/ https://www.ncbi.nlm.nih.gov/pubmed/27348748 http://dx.doi.org/10.1371/journal.ppat.1005720 |
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