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Pegylated Interferon α-2a Triggers NK-Cell Functionality and Specific T-Cell Responses in Patients with Chronic HBV Infection without HBsAg Seroconversion

Pegylated interferon α-2a (Peg-IFN-α) represents a therapeutic alternative to the prolonged use of nucleos(t)ide analog (NA) in chronic hepatitis B (CHB) infection. The mechanisms leading to a positive clinical outcome remain unclear. As immune responses are critical for virus control, we investigat...

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Detalles Bibliográficos
Autores principales: Bruder Costa, Juliana, Dufeu-Duchesne, Tania, Leroy, Vincent, Bertucci, Inga, Bouvier-Alias, Magali, Pouget, Noelle, Brevot-Lutton, Ophelie, Bourliere, Marc, Zoulim, Fabien, Plumas, Joel, Aspord, Caroline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4922676/
https://www.ncbi.nlm.nih.gov/pubmed/27348813
http://dx.doi.org/10.1371/journal.pone.0158297