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Pegylated Interferon α-2a Triggers NK-Cell Functionality and Specific T-Cell Responses in Patients with Chronic HBV Infection without HBsAg Seroconversion
Pegylated interferon α-2a (Peg-IFN-α) represents a therapeutic alternative to the prolonged use of nucleos(t)ide analog (NA) in chronic hepatitis B (CHB) infection. The mechanisms leading to a positive clinical outcome remain unclear. As immune responses are critical for virus control, we investigat...
Autores principales: | Bruder Costa, Juliana, Dufeu-Duchesne, Tania, Leroy, Vincent, Bertucci, Inga, Bouvier-Alias, Magali, Pouget, Noelle, Brevot-Lutton, Ophelie, Bourliere, Marc, Zoulim, Fabien, Plumas, Joel, Aspord, Caroline |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4922676/ https://www.ncbi.nlm.nih.gov/pubmed/27348813 http://dx.doi.org/10.1371/journal.pone.0158297 |
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