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Intrinsic resistance to EGFR tyrosine kinase inhibitors in advanced non-small-cell lung cancer with activating EGFR mutations

Identifying activating EGFR mutations is a useful predictive strategy that helps select a population of advanced non-small-cell lung cancer (NSCLC) patients for treatment with EGFR tyrosine kinase inhibitors (TKIs). Patients with sensitizing EGFR mutations (predominantly an in-frame deletion in exon...

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Detalles Bibliográficos
Autores principales:	Wang, Jun, Wang, Baocheng, Chu, Huili, Yao, Yunfeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2016
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4922765/ https://www.ncbi.nlm.nih.gov/pubmed/27382309 http://dx.doi.org/10.2147/OTT.S106399

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