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Novel Biological Approaches for Testing the Contributions of Single DSBs and DSB Clusters to the Biological Effects of High LET Radiation

The adverse biological effects of ionizing radiation (IR) are commonly attributed to the generation of DNA double-strand breaks (DSBs). IR-induced DSBs are generated by clusters of ionizations, bear damaged terminal nucleotides, and frequently comprise base damages and single-strand breaks in the vi...

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Detalles Bibliográficos
Autores principales:	Mladenova, Veronika, Mladenov, Emil, Iliakis, George
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923065/ https://www.ncbi.nlm.nih.gov/pubmed/27446809 http://dx.doi.org/10.3389/fonc.2016.00163

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