RNA Fluorescence with Light-Up Aptamers

Seeing is not only believing; it also includes understanding. Cellular imaging with GFP in live cells has been transformative in many research fields. Modulation of cellular regulation is tightly regulated and innovative imaging technologies contribute to further understand cellular signaling and ph...

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Detalles Bibliográficos
Autor principal: Ouellet, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923196/
https://www.ncbi.nlm.nih.gov/pubmed/27446908
http://dx.doi.org/10.3389/fchem.2016.00029
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author Ouellet, Jonathan
author_facet Ouellet, Jonathan
author_sort Ouellet, Jonathan
collection PubMed
description Seeing is not only believing; it also includes understanding. Cellular imaging with GFP in live cells has been transformative in many research fields. Modulation of cellular regulation is tightly regulated and innovative imaging technologies contribute to further understand cellular signaling and physiology. New types of genetically encoded biosensors have been developed over the last decade. They are RNA aptamers that bind with their cognate fluorogen ligands and activate their fluorescence. The emergence and the evolution of these RNA aptamers as well as their conversion into a wide spectrum of applications are examined in a global way.
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spelling pubmed-49231962016-07-21 RNA Fluorescence with Light-Up Aptamers Ouellet, Jonathan Front Chem Chemistry Seeing is not only believing; it also includes understanding. Cellular imaging with GFP in live cells has been transformative in many research fields. Modulation of cellular regulation is tightly regulated and innovative imaging technologies contribute to further understand cellular signaling and physiology. New types of genetically encoded biosensors have been developed over the last decade. They are RNA aptamers that bind with their cognate fluorogen ligands and activate their fluorescence. The emergence and the evolution of these RNA aptamers as well as their conversion into a wide spectrum of applications are examined in a global way. Frontiers Media S.A. 2016-06-28 /pmc/articles/PMC4923196/ /pubmed/27446908 http://dx.doi.org/10.3389/fchem.2016.00029 Text en Copyright © 2016 Ouellet. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Chemistry
Ouellet, Jonathan
RNA Fluorescence with Light-Up Aptamers
title RNA Fluorescence with Light-Up Aptamers
title_full RNA Fluorescence with Light-Up Aptamers
title_fullStr RNA Fluorescence with Light-Up Aptamers
title_full_unstemmed RNA Fluorescence with Light-Up Aptamers
title_short RNA Fluorescence with Light-Up Aptamers
title_sort rna fluorescence with light-up aptamers
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923196/
https://www.ncbi.nlm.nih.gov/pubmed/27446908
http://dx.doi.org/10.3389/fchem.2016.00029
work_keys_str_mv AT ouelletjonathan rnafluorescencewithlightupaptamers

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