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Targeted Delivery of C/EBPα -saRNA by Pancreatic Ductal Adenocarcinoma-specific RNA Aptamers Inhibits Tumor Growth In Vivo
The 5-year survival rate for pancreatic ductal adenocarcinoma (PDAC) remains dismal despite current chemotherapeutic agents and inhibitors of molecular targets. As the incidence of PDAC constantly increases, more effective multidrug approaches must be made. Here, we report a novel method of deliveri...
Autores principales: | Yoon, Sorah, Huang, Kai-Wen, Reebye, Vikash, Mintz, Paul, Tien, Yu-Wen, Lai, Hong-Shiee, Sætrom, Pål, Reccia, Isabella, Swiderski, Piotr, Armstrong, Brian, Jozwiak, Agnieszka, Spalding, Duncan, Jiao, Long, Habib, Nagy, Rossi, John J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923325/ https://www.ncbi.nlm.nih.gov/pubmed/26983359 http://dx.doi.org/10.1038/mt.2016.60 |
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