Voriconazole-Induced Periostitis Mimicking Chronic Graft-versus-Host Disease after Allogeneic Stem Cell Transplantation

Voriconazole is an established first-line agent for treatment of invasive fungal infections in patients undergoing allogeneic stem cell transplantation (ASCT). It is associated with the uncommon complication of periostitis. We report this complication in a 58-year-old female undergoing HSCT. She was...

Descripción completa

Detalles Bibliográficos
Autores principales: Sweiss, Karen, Oh, Annie, Rondelli, Damiano, Patel, Pritesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923522/
https://www.ncbi.nlm.nih.gov/pubmed/27403356
http://dx.doi.org/10.1155/2016/3242196
_version_ 1782439726420066304
author Sweiss, Karen
Oh, Annie
Rondelli, Damiano
Patel, Pritesh
author_facet Sweiss, Karen
Oh, Annie
Rondelli, Damiano
Patel, Pritesh
author_sort Sweiss, Karen
collection PubMed
description Voriconazole is an established first-line agent for treatment of invasive fungal infections in patients undergoing allogeneic stem cell transplantation (ASCT). It is associated with the uncommon complication of periostitis. We report this complication in a 58-year-old female undergoing HSCT. She was treated with corticosteroids with minimal improvement. The symptoms related to periostitis can mimic chronic graft-versus-host disease in patients undergoing HSCT and clinicians should differentiate this from other diagnoses and promptly discontinue therapy.
format Online
Article
Text
id pubmed-4923522
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher Hindawi Publishing Corporation
record_format MEDLINE/PubMed
spelling pubmed-49235222016-07-11 Voriconazole-Induced Periostitis Mimicking Chronic Graft-versus-Host Disease after Allogeneic Stem Cell Transplantation Sweiss, Karen Oh, Annie Rondelli, Damiano Patel, Pritesh Case Rep Infect Dis Case Report Voriconazole is an established first-line agent for treatment of invasive fungal infections in patients undergoing allogeneic stem cell transplantation (ASCT). It is associated with the uncommon complication of periostitis. We report this complication in a 58-year-old female undergoing HSCT. She was treated with corticosteroids with minimal improvement. The symptoms related to periostitis can mimic chronic graft-versus-host disease in patients undergoing HSCT and clinicians should differentiate this from other diagnoses and promptly discontinue therapy. Hindawi Publishing Corporation 2016 2016-06-14 /pmc/articles/PMC4923522/ /pubmed/27403356 http://dx.doi.org/10.1155/2016/3242196 Text en Copyright © 2016 Karen Sweiss et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Sweiss, Karen
Oh, Annie
Rondelli, Damiano
Patel, Pritesh
Voriconazole-Induced Periostitis Mimicking Chronic Graft-versus-Host Disease after Allogeneic Stem Cell Transplantation
title Voriconazole-Induced Periostitis Mimicking Chronic Graft-versus-Host Disease after Allogeneic Stem Cell Transplantation
title_full Voriconazole-Induced Periostitis Mimicking Chronic Graft-versus-Host Disease after Allogeneic Stem Cell Transplantation
title_fullStr Voriconazole-Induced Periostitis Mimicking Chronic Graft-versus-Host Disease after Allogeneic Stem Cell Transplantation
title_full_unstemmed Voriconazole-Induced Periostitis Mimicking Chronic Graft-versus-Host Disease after Allogeneic Stem Cell Transplantation
title_short Voriconazole-Induced Periostitis Mimicking Chronic Graft-versus-Host Disease after Allogeneic Stem Cell Transplantation
title_sort voriconazole-induced periostitis mimicking chronic graft-versus-host disease after allogeneic stem cell transplantation
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923522/
https://www.ncbi.nlm.nih.gov/pubmed/27403356
http://dx.doi.org/10.1155/2016/3242196
work_keys_str_mv AT sweisskaren voriconazoleinducedperiostitismimickingchronicgraftversushostdiseaseafterallogeneicstemcelltransplantation
AT ohannie voriconazoleinducedperiostitismimickingchronicgraftversushostdiseaseafterallogeneicstemcelltransplantation
AT rondellidamiano voriconazoleinducedperiostitismimickingchronicgraftversushostdiseaseafterallogeneicstemcelltransplantation
AT patelpritesh voriconazoleinducedperiostitismimickingchronicgraftversushostdiseaseafterallogeneicstemcelltransplantation

Ejemplares similares