Circular Helix-Like Curve: An Effective Tool of Biological Sequence Analysis and Comparison

This paper constructed a novel injection from a DNA sequence to a 3D graph, named circular helix-like curve (CHC). The presented graphical representation is available for visualizing characterizations of a single DNA sequence and identifying similarities and differences among several DNAs. A 12-dime...

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Detalles Bibliográficos
Autores principales: Li, Yushuang, Xiao, Wenli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923644/
https://www.ncbi.nlm.nih.gov/pubmed/27403205
http://dx.doi.org/10.1155/2016/3262813
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author Li, Yushuang
Xiao, Wenli
author_facet Li, Yushuang
Xiao, Wenli
author_sort Li, Yushuang
collection PubMed
description This paper constructed a novel injection from a DNA sequence to a 3D graph, named circular helix-like curve (CHC). The presented graphical representation is available for visualizing characterizations of a single DNA sequence and identifying similarities and differences among several DNAs. A 12-dimensional vector extracted from CHC, as a numerical characterization of CHC, was applied to analyze phylogenetic relationships of 11 species, 74 ribosomal RNAs, 48 Hepatitis E viruses, and 18 eutherian mammals, respectively. Successful experiments illustrated that CHC is an effective tool of biological sequence analysis and comparison.
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spelling pubmed-49236442016-07-11 Circular Helix-Like Curve: An Effective Tool of Biological Sequence Analysis and Comparison Li, Yushuang Xiao, Wenli Comput Math Methods Med Research Article This paper constructed a novel injection from a DNA sequence to a 3D graph, named circular helix-like curve (CHC). The presented graphical representation is available for visualizing characterizations of a single DNA sequence and identifying similarities and differences among several DNAs. A 12-dimensional vector extracted from CHC, as a numerical characterization of CHC, was applied to analyze phylogenetic relationships of 11 species, 74 ribosomal RNAs, 48 Hepatitis E viruses, and 18 eutherian mammals, respectively. Successful experiments illustrated that CHC is an effective tool of biological sequence analysis and comparison. Hindawi Publishing Corporation 2016 2016-06-14 /pmc/articles/PMC4923644/ /pubmed/27403205 http://dx.doi.org/10.1155/2016/3262813 Text en Copyright © 2016 Y. Li and W. Xiao. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Li, Yushuang
Xiao, Wenli
Circular Helix-Like Curve: An Effective Tool of Biological Sequence Analysis and Comparison
title Circular Helix-Like Curve: An Effective Tool of Biological Sequence Analysis and Comparison
title_full Circular Helix-Like Curve: An Effective Tool of Biological Sequence Analysis and Comparison
title_fullStr Circular Helix-Like Curve: An Effective Tool of Biological Sequence Analysis and Comparison
title_full_unstemmed Circular Helix-Like Curve: An Effective Tool of Biological Sequence Analysis and Comparison
title_short Circular Helix-Like Curve: An Effective Tool of Biological Sequence Analysis and Comparison
title_sort circular helix-like curve: an effective tool of biological sequence analysis and comparison
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923644/
https://www.ncbi.nlm.nih.gov/pubmed/27403205
http://dx.doi.org/10.1155/2016/3262813
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AT xiaowenli circularhelixlikecurveaneffectivetoolofbiologicalsequenceanalysisandcomparison

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