Lateral Temporal Lobe: An Early Imaging Marker of the Presymptomatic GRN Disease?

The preclinical stage of frontotemporal lobar degeneration (FTLD) is not well characterized. We conducted a brain metabolism (FDG-PET) and structural (cortical thickness) study to detect early changes in asymptomatic GRN mutation carriers (aGRN+) that were evaluated longitudinally over a 20-month pe...

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Detalles Bibliográficos
Autores principales: Caroppo, Paola, Habert, Marie-Odile, Durrleman, Stanley, Funkiewiez, Aurélie, Perlbarg, Vincent, Hahn, Valérie, Bertin, Hugo, Gaubert, Malo, Routier, Alexandre, Hannequin, Didier, Deramecourt, Vincent, Pasquier, Florence, Rivaud-Pechoux, Sophie, Vercelletto, Martine, Edouart, Geoffrey, Valabregue, Romain, Lejeune, Pascal, Didic, Mira, Corvol, Jean-Christophe, Benali, Habib, Lehericy, Stephane, Dubois, Bruno, Colliot, Olivier, Brice, Alexis, Le Ber, Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923734/
https://www.ncbi.nlm.nih.gov/pubmed/26401709
http://dx.doi.org/10.3233/JAD-150270

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