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Involvement of the GABAergic system in the neuroprotective and sedative effects of acacetin 7-O-glucoside in rodents

Purpose: Characterization of sedative, possible anticonvulsant, and protective effects of Acacetin-7-O-glucoside (7-ACAG). Methods: 7-ACAG was separated and its purity was analyzed. Its sedative and anti-seizure effects (1, 10, 20, and 40 mg/kg) were evaluated in male mice. Synaptic responses were a...

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Detalles Bibliográficos
Autores principales: Gálvez, Javier, Estrada-Reyes, Rosa, Benítez-King, Gloria, Araujo, Gabriela, Orozco, Sandra, Fernández-Mas, Rodrigo, Almazán, Salvador, Calixto, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923766/
https://www.ncbi.nlm.nih.gov/pubmed/26410208
http://dx.doi.org/10.3233/RNN-140486