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Bacterial evolution in PCD and CF patients follows the same mutational steps

Infections with Pseudomonas aeruginosa increase morbidity in primary ciliary dyskinesia (PCD) and cystic fibrosis (CF) patients. Both diseases are associated with a defect of the mucociliary clearance; in PCD caused by non-functional cilia, in CF by changed mucus. Whole genome sequencing of P. aerug...

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Detalles Bibliográficos
Autores principales:	Sommer, Lea M., Alanin, Mikkel Christian, Marvig, Rasmus L., Nielsen, Kim Gjerum, Høiby, Niels, von Buchwald, Christian, Molin, Søren, Johansen, Helle Krogh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923847/ https://www.ncbi.nlm.nih.gov/pubmed/27349973 http://dx.doi.org/10.1038/srep28732

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