CXCL10-Mediates Macrophage, but not Other Innate Immune Cells-Associated Inflammation in Murine Nonalcoholic Steatohepatitis

Nonalcoholic steatohepatitis (NASH) is an inflammatory lipotoxic disorder, but how inflammatory cells are recruited and activated within the liver is still unclear. We previously reported that lipotoxic hepatocytes release CXCL10-enriched extracellular vesicles, which are potently chemotactic for ce...

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Detalles Bibliográficos
Autores principales: Tomita, Kyoko, Freeman, Brittany L., Bronk, Steven F., LeBrasseur, Nathan K., White, Thomas A., Hirsova, Petra, Ibrahim, Samar H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923862/
https://www.ncbi.nlm.nih.gov/pubmed/27349927
http://dx.doi.org/10.1038/srep28786

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