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Spontaneous mutations in Streptococcus pyogenes isolates from streptococcal toxic shock syndrome patients play roles in virulence
Streptococcus pyogenes (group A Streptococcus; GAS) is a widespread human pathogen and causes streptococcal toxic shock syndrome (STSS). STSS isolates have been previously shown to have high frequency mutations in the csrS/csrR (covS/covR) and/or rgg (ropB) genes, which are negative regulators of vi...
Autores principales: | Ikebe, Tadayoshi, Matsumura, Takayuki, Nihonmatsu, Hisako, Ohya, Hitomi, Okuno, Rumi, Mitsui, Chieko, Kawahara, Ryuji, Kameyama, Mitsuhiro, Sasaki, Mari, Shimada, Naomi, Ato, Manabu, Ohnishi, Makoto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923885/ https://www.ncbi.nlm.nih.gov/pubmed/27349341 http://dx.doi.org/10.1038/srep28761 |
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