Differential induction of muscle atrophy pathways in two mouse models of spinal muscular atrophy

Motor neuron loss and neurogenic atrophy are hallmarks of spinal muscular atrophy (SMA), a leading genetic cause of infant deaths. Previous studies have focused on deciphering disease pathogenesis in motor neurons. However, a systematic evaluation of atrophy pathways in muscles is lacking. Here, we...

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Detalles Bibliográficos
Autores principales: Deguise, Marc-Olivier, Boyer, Justin G., McFall, Emily R., Yazdani, Armin, De Repentigny, Yves, Kothary, Rashmi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924104/
https://www.ncbi.nlm.nih.gov/pubmed/27349908
http://dx.doi.org/10.1038/srep28846

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