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Salvianolic Acid B Inhibits Aβ Generation by Modulating BACE1 Activity in SH-SY5Y-APPsw Cells

Alzheimer’s disease (AD) is a neurodegenerative disease in humans. The accumulation of amyloid-β (Aβ) plays a critical role in the pathogenesis of AD. Previous studies indicated that Salvianolic acid B (SalB) could ameliorate Aβ-induced memory impairment. However, whether SalB could influence the ge...

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Detalles Bibliográficos
Autores principales: Tang, Ying, Huang, Dan, Zhang, Mei-Hua, Zhang, Wen-Sheng, Tang, Yu-Xin, Shi, Zheng-Xiang, Deng, Li, Zhou, Dai-Han, Lu, Xin-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924174/
https://www.ncbi.nlm.nih.gov/pubmed/27258307
http://dx.doi.org/10.3390/nu8060333