Frequency of BRAF V600E mutations in 969 central nervous system neoplasms

BACKGROUND: Treatment options for oncological diseases have been enhanced by the advent of targeted therapies. The point mutation of the BRAF gene at codon 600 (BRAF V600E) is found in several tumor entities and can be approached with selective inhibitory antibodies. The BRAF inhibitor vemurafenib h...

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Detalles Bibliográficos
Autores principales: Behling, Felix, Barrantes-Freer, Alonso, Skardelly, Marco, Nieser, Maike, Christians, Arne, Stockhammer, Florian, Rohde, Veit, Tatagiba, Marcos, Hartmann, Christian, Stadelmann, Christine, Schittenhelm, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924254/
https://www.ncbi.nlm.nih.gov/pubmed/27350555
http://dx.doi.org/10.1186/s13000-016-0506-2

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