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MT5-MMP, just a new APP processing proteinase in Alzheimer’s disease?

We have recently identified in a transgenic mouse model of Alzheimer’s disease (AD) membrane-type 5-MMP (MT5-MMP) as a new player in Alzheimer’s pathogenesis, which displays pro-amyloidogenic features and proteolytic processing of amyloid precursor protein (APP). Another group has reported that MT5-...

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Detalles Bibliográficos
Autores principales:	Baranger, Kévin, Khrestchatisky, Michel, Rivera, Santiago
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Hypothesis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924292/ https://www.ncbi.nlm.nih.gov/pubmed/27349644 http://dx.doi.org/10.1186/s12974-016-0633-4

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