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Activation of a plasmid-situated type III PKS gene cluster by deletion of a wbl gene in deepsea-derived Streptomyces somaliensis SCSIO ZH66

BACKGROUND: Actinomycete genome sequencing has disclosed a large number of cryptic secondary metabolite biosynthetic gene clusters. However, their unavailable or limited expression severely hampered the discovery of bioactive compounds. The whiB-like (wbl) regulatory genes play important roles in mo...

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Detalles Bibliográficos
Autores principales:	Huang, Huiming, Hou, Lukuan, Li, Huayue, Qiu, Yanhong, Ju, Jianhua, Li, Wenli
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924298/ https://www.ncbi.nlm.nih.gov/pubmed/27350607 http://dx.doi.org/10.1186/s12934-016-0515-6

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