Intratumoral heterogeneity as a source of discordance in breast cancer biomarker classification

BACKGROUND: Spatial heterogeneity in biomarker expression may impact breast cancer classification. The aims of this study were to estimate the frequency of spatial heterogeneity in biomarker expression within tumors, to identify technical and biological factors contributing to spatial heterogeneity,...

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Detalles Bibliográficos
Autores principales: Allott, Emma H., Geradts, Joseph, Sun, Xuezheng, Cohen, Stephanie M., Zirpoli, Gary R., Khoury, Thaer, Bshara, Wiam, Chen, Mengjie, Sherman, Mark E., Palmer, Julie R., Ambrosone, Christine B., Olshan, Andrew F., Troester, Melissa A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924300/
https://www.ncbi.nlm.nih.gov/pubmed/27349894
http://dx.doi.org/10.1186/s13058-016-0725-1

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