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Combinatorial strategies based on CRAd-IL24 and CRAd-ING4 virotherapy with anti-angiogenesis treatment for ovarian cancer
BACKGROUND: A major hurdle incurrent to the human clinical application of conditionally replicative adenovirus (CRAd)-based virotherapy agents is their limited therapeutic efficacy. In this study we evaluated whether arming our previously reported Ad5/3Δ24 CRAd vector containing a 24-base pair delet...
Autores principales: | Ashshi, Ahmad Mohammad, El-Shemi, Adel Galal, Dmitriev, Igor P., Kashentseva, Elena A., Curiel, David T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924320/ https://www.ncbi.nlm.nih.gov/pubmed/27349517 http://dx.doi.org/10.1186/s13048-016-0248-5 |
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