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5-azacytidine induces transcriptome changes in Escherichia coli via DNA methylation-dependent and DNA methylation-independent mechanisms
BACKGROUND: Escherichia coli K-12 strains contain DNA cytosine methyltransferase (Dcm), which generates 5-methylcytosine at 5′CCWGG3′ sites. Although the role of 5-methylcytosine in eukaryotic gene expression is relatively well described, the role of 5-methylcytosine in bacterial gene expression is...
Autores principales: | Militello, Kevin T., Simon, Robert D., Mandarano, Alexandra H., DiNatale, Anthony, Hennick, Stacy M., Lazatin, Justine C., Cantatore, Sarah |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924334/ https://www.ncbi.nlm.nih.gov/pubmed/27349222 http://dx.doi.org/10.1186/s12866-016-0741-4 |
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