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Guardian of the Human Genome: Host Defense Mechanisms against LINE-1 Retrotransposition
Long interspersed element type 1 (LINE-1, L1) is a mobile genetic element comprising about 17% of the human genome, encoding a newly identified ORF0 with unknown function, ORF1p with RNA-binding activity and ORF2p with endonuclease and reverse transcriptase activities required for L1 retrotransposit...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924340/ https://www.ncbi.nlm.nih.gov/pubmed/27446907 http://dx.doi.org/10.3389/fchem.2016.00028 |