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Laparoscopic surgery for patients with colorectal cancer produces better short‐term outcomes with similar survival outcomes in elderly patients compared to open surgery

The number of operations on elderly colorectal cancer (CRC) patients has increased with the aging of the population. The aim of this study was to evaluate surgical outcomes in elderly patients who underwent laparoscopic or open surgery for CRC. We analyzed the data of 280 patients aged 80 or over wh...

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Autores principales: Moon, Soo Yun, Kim, Sohee, Lee, Soo Young, Han, Eon Chul, Kang, Sung‐Bum, Jeong, Seung‐Yong, Park, Kyu Joo, Oh, Jae Hwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924362/
https://www.ncbi.nlm.nih.gov/pubmed/26923309
http://dx.doi.org/10.1002/cam4.671
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author Moon, Soo Yun
Kim, Sohee
Lee, Soo Young
Han, Eon Chul
Kang, Sung‐Bum
Jeong, Seung‐Yong
Park, Kyu Joo
Oh, Jae Hwan
author_facet Moon, Soo Yun
Kim, Sohee
Lee, Soo Young
Han, Eon Chul
Kang, Sung‐Bum
Jeong, Seung‐Yong
Park, Kyu Joo
Oh, Jae Hwan
author_sort Moon, Soo Yun
collection PubMed
description The number of operations on elderly colorectal cancer (CRC) patients has increased with the aging of the population. The aim of this study was to evaluate surgical outcomes in elderly patients who underwent laparoscopic or open surgery for CRC. We analyzed the data of 280 patients aged 80 or over who underwent surgery for CRC between January 2001 and December 2010. Seventy‐one pairs were selected after propensity score matching for laparoscopic or open surgery. Operative time, return to normal bowel function, length of hospital stay, postoperative complications, overall survival (OS), recurrence‐free survival (RFS), and prognostic factors affecting survival were investigated. In matched cohorts, operative time in the laparoscopic group was longer than in the open group (P < 0.001). In the laparoscopic group, time to flatus passage (P < 0.001) and length of postoperative hospital stay (P = 0.037) were shorter than in the open group. The rate of operation‐related morbidity was higher in the open group (P = 0.019). There was no difference in OS and RFS between two groups. This study suggests that laparoscopic surgery for CRC in elderly patients may be safe and feasible, with better short‐term outcomes. OS and RFS, however, were not different in both groups.
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spelling pubmed-49243622016-06-29 Laparoscopic surgery for patients with colorectal cancer produces better short‐term outcomes with similar survival outcomes in elderly patients compared to open surgery Moon, Soo Yun Kim, Sohee Lee, Soo Young Han, Eon Chul Kang, Sung‐Bum Jeong, Seung‐Yong Park, Kyu Joo Oh, Jae Hwan Cancer Med Clinical Cancer Research The number of operations on elderly colorectal cancer (CRC) patients has increased with the aging of the population. The aim of this study was to evaluate surgical outcomes in elderly patients who underwent laparoscopic or open surgery for CRC. We analyzed the data of 280 patients aged 80 or over who underwent surgery for CRC between January 2001 and December 2010. Seventy‐one pairs were selected after propensity score matching for laparoscopic or open surgery. Operative time, return to normal bowel function, length of hospital stay, postoperative complications, overall survival (OS), recurrence‐free survival (RFS), and prognostic factors affecting survival were investigated. In matched cohorts, operative time in the laparoscopic group was longer than in the open group (P < 0.001). In the laparoscopic group, time to flatus passage (P < 0.001) and length of postoperative hospital stay (P = 0.037) were shorter than in the open group. The rate of operation‐related morbidity was higher in the open group (P = 0.019). There was no difference in OS and RFS between two groups. This study suggests that laparoscopic surgery for CRC in elderly patients may be safe and feasible, with better short‐term outcomes. OS and RFS, however, were not different in both groups. John Wiley and Sons Inc. 2016-02-29 /pmc/articles/PMC4924362/ /pubmed/26923309 http://dx.doi.org/10.1002/cam4.671 Text en © 2016 The Authors. Cancer Medicine published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Cancer Research
Moon, Soo Yun
Kim, Sohee
Lee, Soo Young
Han, Eon Chul
Kang, Sung‐Bum
Jeong, Seung‐Yong
Park, Kyu Joo
Oh, Jae Hwan
Laparoscopic surgery for patients with colorectal cancer produces better short‐term outcomes with similar survival outcomes in elderly patients compared to open surgery
title Laparoscopic surgery for patients with colorectal cancer produces better short‐term outcomes with similar survival outcomes in elderly patients compared to open surgery
title_full Laparoscopic surgery for patients with colorectal cancer produces better short‐term outcomes with similar survival outcomes in elderly patients compared to open surgery
title_fullStr Laparoscopic surgery for patients with colorectal cancer produces better short‐term outcomes with similar survival outcomes in elderly patients compared to open surgery
title_full_unstemmed Laparoscopic surgery for patients with colorectal cancer produces better short‐term outcomes with similar survival outcomes in elderly patients compared to open surgery
title_short Laparoscopic surgery for patients with colorectal cancer produces better short‐term outcomes with similar survival outcomes in elderly patients compared to open surgery
title_sort laparoscopic surgery for patients with colorectal cancer produces better short‐term outcomes with similar survival outcomes in elderly patients compared to open surgery
topic Clinical Cancer Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924362/
https://www.ncbi.nlm.nih.gov/pubmed/26923309
http://dx.doi.org/10.1002/cam4.671
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