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Hypoxia‐responsive miR‐124 and miR‐144 reduce hypoxia‐induced autophagy and enhance radiosensitivity of prostate cancer cells via suppressing PIM1
Cancer cells in hypoxia usually make adaptive changes in cellular metabolism, such as altered autophagy. This might be a cause of enhanced radioresistance in some types of cancer. In this study, we investigated hypoxia‐responsive miRNAs in two prostate cancer cell lines (DU145 and PC3). This study f...
Autores principales: | Gu, Hao, Liu, Mingzhu, Ding, Changmao, Wang, Xin, Wang, Rui, Wu, Xinyu, Fan, Ruitai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924376/ https://www.ncbi.nlm.nih.gov/pubmed/26990493 http://dx.doi.org/10.1002/cam4.664 |
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