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Significance of KRAS, NRAS, BRAF and PIK3CA mutations in metastatic colorectal cancer patients receiving Bevacizumab: a single institution experience
Background. KRAS mutation is an important predictive and prognostic factor for patients receiving anti-EGFR therapy. An expanded KRAS, NRAS, BRAF, PIK3CA mutation analysis provides additional prognostic information, but its role in predicting bevacizumab efficacy is unclear. The aim of our study was...
Autores principales: | Baltruškevičienė, Edita, Mickys, Ugnius, Žvirblis, Tadas, Stulpinas, Rokas, Pipirienė Želvienė, Teresė, Aleknavičius, Eduardas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lithuanian Academy of Sciences Publishers
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924637/ https://www.ncbi.nlm.nih.gov/pubmed/28356789 http://dx.doi.org/10.6001/actamedica.v23i1.3267 |
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