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FGF19 promotes epithelial-mesenchymal transition in hepatocellular carcinoma cells by modulating the GSK3β/β- catenin signaling cascade via FGFR4 activation

Compelling evidence suggests that the epithelial-mesenchymal transition (EMT) correlates with aggressiveness of tumors and poor survival. FGF19 has been shown to be involved in EMT in cholangiocarcinoma and colorectal cancer, however, molecular mechanisms underlying FGF19-induced EMT process in hepa...

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Detalles Bibliográficos
Autores principales: Zhao, Huakan, Lv, Fenglin, Liang, Guizhao, Huang, Xiaobin, Wu, Gang, Zhang, Wenfa, Yu, Le, Shi, Lei, Teng, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924662/
https://www.ncbi.nlm.nih.gov/pubmed/26498355
http://dx.doi.org/10.18632/oncotarget.6185