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FGF19 promotes epithelial-mesenchymal transition in hepatocellular carcinoma cells by modulating the GSK3β/β- catenin signaling cascade via FGFR4 activation
Compelling evidence suggests that the epithelial-mesenchymal transition (EMT) correlates with aggressiveness of tumors and poor survival. FGF19 has been shown to be involved in EMT in cholangiocarcinoma and colorectal cancer, however, molecular mechanisms underlying FGF19-induced EMT process in hepa...
Autores principales: | Zhao, Huakan, Lv, Fenglin, Liang, Guizhao, Huang, Xiaobin, Wu, Gang, Zhang, Wenfa, Yu, Le, Shi, Lei, Teng, Yong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924662/ https://www.ncbi.nlm.nih.gov/pubmed/26498355 http://dx.doi.org/10.18632/oncotarget.6185 |
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