GADD45α and γ interaction with CDK11p58 regulates SPDEF protein stability and SPDEF-mediated effects on cancer cell migration

The epithelium-specific Ets transcription factor, SPDEF, plays a critical role in metastasis of prostate and breast cancer cells. While enhanced SPDEF expression blocks migration and invasion, knockdown of SPDEF expression enhances migration, invasion, and metastasis of cancer cells. SPDEF expressio...

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Detalles Bibliográficos
Autores principales: Tamura, Rodrigo E., Paccez, Juliano D., Duncan, Kristal C., Morale, Mirian G., Simabuco, Fernando M., Dillon, Simon, Correa, Ricardo G., Gu, Xuesong, Libermann, Towia A., Zerbini, Luiz F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924684/
https://www.ncbi.nlm.nih.gov/pubmed/26885618
http://dx.doi.org/10.18632/oncotarget.7355

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924684/
https://www.ncbi.nlm.nih.gov/pubmed/26885618
http://dx.doi.org/10.18632/oncotarget.7355

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