Cargando…
GADD45α and γ interaction with CDK11p58 regulates SPDEF protein stability and SPDEF-mediated effects on cancer cell migration
The epithelium-specific Ets transcription factor, SPDEF, plays a critical role in metastasis of prostate and breast cancer cells. While enhanced SPDEF expression blocks migration and invasion, knockdown of SPDEF expression enhances migration, invasion, and metastasis of cancer cells. SPDEF expressio...
Autores principales: | Tamura, Rodrigo E., Paccez, Juliano D., Duncan, Kristal C., Morale, Mirian G., Simabuco, Fernando M., Dillon, Simon, Correa, Ricardo G., Gu, Xuesong, Libermann, Towia A., Zerbini, Luiz F. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924684/ https://www.ncbi.nlm.nih.gov/pubmed/26885618 http://dx.doi.org/10.18632/oncotarget.7355 |
Ejemplares similares
-
Upregulation of SPDEF is associated with poor prognosis in prostate cancer
por: Meiners, Jan, et al.
Publicado: (2019) -
Transcriptional Regulation by ATOH1 and its Target SPDEF in the Intestine
por: Lo, Yuan-Hung, et al.
Publicado: (2016) -
Regulation of SPDEF expression by DNA methylation in advanced prostate cancer
por: Vatanmakanian, Mousa, et al.
Publicado: (2023) -
Inactivation of GSK3β and activation of NF-κB pathway via Axl represents an important mediator of tumorigenesis in esophageal squamous cell carcinoma
por: Paccez, Juliano D., et al.
Publicado: (2015) -
The subtype‐specific molecular function of SPDEF in breast cancer and insights into prognostic significance
por: Ye, Ting, et al.
Publicado: (2021)