Distinct features between MLH1-methylated and unmethylated colorectal carcinomas with the CpG island methylator phenotype: implications in the serrated neoplasia pathway

The presence or absence of MLH1 methylation may critically affect the heterogeneity of colorectal carcinoma (CRC) with the CpG island methylator phenotype (CIMP). Here, we investigated the differential characteristics of CIMP-high (CIMP-H) CRCs according to MLH1 methylation status. To further confir...

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Detalles Bibliográficos
Autores principales: Kim, Jung Ho, Bae, Jeong Mo, Cho, Nam-Yun, Kang, Gyeong Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924700/
https://www.ncbi.nlm.nih.gov/pubmed/26883113
http://dx.doi.org/10.18632/oncotarget.7374

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924700/
https://www.ncbi.nlm.nih.gov/pubmed/26883113
http://dx.doi.org/10.18632/oncotarget.7374

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