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Expression of GADS enhances FLT3-induced mitogenic signaling
GADS is a member of a family of SH2 and SH3 domain-containing adaptors that functions in tyrosine kinase-mediated signaling cascades. Its expression is largely restricted to hematopoietic tissues and cell lines. Therefore, GADS is mainly involved in leukocyte-specific protein tyrosine kinase signali...
Autores principales: | Chougule, Rohit A., Cordero, Eugenia, Moharram, Sausan A., Pietras, Kristian, Rönnstrand, Lars, Kazi, Julhash U. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924701/ https://www.ncbi.nlm.nih.gov/pubmed/26895103 http://dx.doi.org/10.18632/oncotarget.7415 |
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