Longitudinal tracking of subpopulation dynamics and molecular changes during LNCaP cell castration and identification of inhibitors that could target the PSA−/lo castration-resistant cells

We have recently demonstrated that the undifferentiated PSA(−/lo) prostate cancer (PCa) cell population harbors self-renewing long-term tumor-propagating cells that are refractory to castration, thus representing a therapeutic target. Our goals here are, by using the same lineage-tracing reporter sy...

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Detalles Bibliográficos
Autores principales: Rycaj, Kiera, Cho, Eun Jeong, Liu, Xin, Chao, Hsueh-Ping, Liu, Bigang, Li, Qiuhui, Devkota, Ashwini K., Zhang, Dingxiao, Chen, Xin, Moore, John, Dalby, Kevin N., Tang, Dean G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924710/
https://www.ncbi.nlm.nih.gov/pubmed/26871947
http://dx.doi.org/10.18632/oncotarget.7303

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