Overexpression of TSC-22 (transforming growth factor-β-stimulated clone-22) causes marked obesity, splenic abnormality and B cell lymphoma in transgenic mice

In this study, we generated transgenic (Tg) mice, which overexpressed transforming growth factor (TGF)-β stimulated clone-22 (TSC-22), and investigate the functional role of TSC-22 on their development and pathogenesis. We obtained 13 Tg-founders (two mice from C57BL6/J and 11 mice from BDF1). Three...

Descripción completa

Detalles Bibliográficos
Autores principales: Uchida, Daisuke, Kawamata, Hitoshi, Omotehara, Fumie, Miwa, Yoshihiro, Horiuchi, Hideki, Furihata, Tadashi, Tachibana, Masatsugu, Fujimori, Takahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924717/
https://www.ncbi.nlm.nih.gov/pubmed/26872059
http://dx.doi.org/10.18632/oncotarget.7308

Ejemplares similares

Ejemplares similares